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Preparations
Zimar
The antimicrobial drug Zimar is a fluoroquinolone drug. The active ingredient is gatifloxacin.
ATC classification
Indications Zimar
Zimar is used to treat bacterial conjunctivitis caused by sensitive microbes.
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Release form
Zimar is a solution that is available in the form of eye drops, 0.3% 5 ml.
It has the appearance of a transparent liquid with a slight yellowish or greenish tint.
Pharmacodynamics
Zimar is active against various gram-negative and gram-positive microorganisms. The antimicrobial action of the drug is to inhibit the enzymes of pathogenic microorganisms. DNA gyrase is a complex enzyme involved in the processes of replication, transcription and restoration of microbial DNA.
Zimar is active against staphylococci, streptococci, Escherichia coli, Klebsiella, Haemophilus influenzae, Moraxella, Neucheria, Proteus, Chlamydia, Legionella, Mycoplasma, and Peptostreptococci.
Dosing and administration
Locally. The drug is instilled during waking hours.
On the 1st and 2nd day, instill 1 drop into the affected eye every 2 hours, up to 8 times a day. From the 3rd to the 7th day, instill 1 drop up to 4 times a day.
Use Zimar during pregnancy
Zimar is prohibited for use during pregnancy.
Side effects Zimar
The following clinical manifestations were detected during treatment with Zimar:
- allergy in the form of edema, vesicular, bullous or papular rash;
- dyspepsia, bloating, gastritis, mucosal ulcers, gastric bleeding;
- headaches, dizziness, anxiety, irritability, sleep disturbances, tremors and numbness in the limbs, convulsions, panic attacks, changes in taste, hyperesthesia, photophobia;
- increased or decreased heart rate, increased blood pressure, cyanosis;
- difficulty breathing, pharyngitis;
- urinary disorders, blood in the urine;
- bone and joint pain, dry mouth, fever, dry skin and mucous membranes, metrorrhagia, hypoglycemia.
Overdose
Symptoms of a Zimar overdose include slow breathing, nausea, tremors, and cramps in the limbs.
Storage conditions
Zimar is stored in a dark place. The room temperature should not exceed +30°C. Freezing the medicine is prohibited.
Children should not be allowed near places where medicines are stored.
Shelf life
Zimar is approved for storage for two years.